Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARF6 | P62330 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329050 | 0.90 | ARF6 (0.35) | ARF6XDHCXCR2KDM1AALDH1A1 | |
| SCHEMBL27329142 | 0.87 | CXCR2 (0.35) | ARF6XDHCXCR2KDM1AALDH1A1 | |
| SCHEMBL27329549 | 0.86 | MEN1 (0.31) | MEN1KMT2AXDHPSDALOX12 | |
| SCHEMBL27329187 | 0.84 | HPGD (0.34) | ARF6XDHALDH1A1 | |
| SCHEMBL30992355 | 0.83 | MAPKAPK2 (0.32) | — | |
| SCHEMBL27329679 | 0.82 | KDM1A (0.40) | MEN1KMT2AXDHPTGS2CXCR2 | |
| SCHEMBL27329693 | 0.82 | ALDH1A1 (0.37) | MEN1KMT2AXDHPTGS2KDM1A | |
| SCHEMBL27329696 | 0.81 | XDH (0.34) | MEN1KMT2AXDHPTGS2KDM1A | |
| SCHEMBL27329413 | 0.81 | HAVCR2 (0.37) | MEN1KMT2AXDHPTGS2KDM1A | |
| SCHEMBL27329160 | 0.81 | ADORA2A (0.32) | XDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129881-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | WAVEBREAK THERAPEUTICS LIMITED (US) | 2024-06-20 | — | — | WO | disclosed |