Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329913 | 0.81 | PKM (0.36) | MAPK1PKM | |
| SCHEMBL868914 | 0.80 | GPR119 (0.54) | POLBMAPTDTYMKGPR119NR1H2 | |
| SCHEMBL27329287 | 0.77 | NAMPT (0.47) | POLBMAPTGPR119NR1H2MAPK1 | |
| SCHEMBL27329813 | 0.76 | POLB (0.44) | POLBMAPTDTYMKGPR119NR1H2 | |
| SCHEMBL1583147 | 0.76 | GPR119 (0.58) | POLBMAPTDTYMKGPR119MAPK1 | |
| SCHEMBL1663068 | 0.76 | GRM5 (0.51) | POLBMAPTDTYMKGPR119NR1H2 | |
| SCHEMBL28597591 | 0.75 | GPR119 (0.58) | POLBMAPTDTYMKGPR119NR1H2 | |
| SCHEMBL1664318 | 0.74 | GPR119 (0.43) | POLBMAPTGPR119NR1H2MAPK1 | |
| SCHEMBL948878 | 0.73 | GPR119 (0.53) | POLBMAPTGPR119DDB1CRBN | |
| SCHEMBL14845641 | 0.73 | MAPT (0.48) | POLBMAPTGPR119NR1H2CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |