Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27336625 | 0.94 | HTT (0.52) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL17938153 | 0.84 | HTT (0.39) | HTTHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL27632867 | 0.74 | GSK3B (0.37) | HTTHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL27332910 | 0.73 | HTT (0.59) | HTTHSD17B10MAPTGAAKMT2A | |
| Hydrochloric Acid SCHEMBL27393238 | 0.73 | HTT (0.59) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL927943 | 0.70 | NCF1 (0.34) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL28135536 | 0.70 | ALDH1A1 (0.62) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL27370005 | 0.70 | HTT (0.55) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL11858611 | 0.68 | MAPT (0.65) | HTTHSD17B10MAPTGAAKMT2A | |
| SCHEMBL31364062 | 0.67 | TNK2 (0.44) | MAPTGAAALDH1A1TNK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043993-C | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1999-07-07 | — | — | CN | disclosed |
| CN-1156455-A | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMACUEITCAL CO L (JP) | 1997-08-06 | — | — | CN | disclosed |