Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 4/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27332913 | 0.84 | HTT (0.55) | HTTHSD17B10HDAC3HDAC4HDAC7 | |
| SCHEMBL16836547 | 0.81 | BTK (0.41) | — | |
| SCHEMBL27632867 | 0.79 | GSK3B (0.37) | HTTHSD17B10KDM5AKDM5BKDM4A | |
| SCHEMBL27336625 | 0.79 | HTT (0.52) | HTTHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL927943 | 0.75 | NCF1 (0.34) | HTTHSD17B10KDM4EKMT2AMEN1 | |
| SCHEMBL11895141 | 0.74 | HTT (0.42) | HTTHSD17B10KDM5AKDM5BGABRP | |
| SCHEMBL28002669 | 0.74 | SCN10A (0.41) | HSD17B10HDAC3KDM4EKMT2AMEN1 | |
| SCHEMBL22688908 | 0.74 | NAPRT (0.48) | HTTHSD17B10KDM5AKDM5BGABRP | |
| SCHEMBL1243693 | 0.72 | KDM4E (0.50) | HTTHSD17B10KDM5AKDM5BGABRP | |
| SCHEMBL29860445 | 0.72 | KDM4E (0.50) | HTTHSD17B10KDM5AKDM5BGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016118586-A1 | LOWCOST, HIGH YIELD SYNTHESIS OF NEVIRAPINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016118586-A1 | LOWCOST, HIGH YIELD SYNTHESIS OF NEVIRAPINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-07-28 | — | — | WO | disclosed |