Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733449 | 1.00 | TPH1 (0.76) | TPH1 | |
| SCHEMBL869852 | 0.86 | TPH1 (0.81) | TPH1 | |
| SCHEMBL869853 | 0.86 | TPH1 (0.81) | TPH1 | |
| SCHEMBL1870002 | 0.79 | TPH1 (0.68) | TPH1 | |
| SCHEMBL307395 | 0.79 | TPH1 (1.00) | TPH1 | |
| SCHEMBL309002 | 0.79 | TPH1 (1.00) | TPH1 | |
| SCHEMBL1873079 | 0.77 | TPH1 (0.83) | TPH1 | |
| SCHEMBL2733443 | 0.77 | TPH1 (0.59) | TPH1 | |
| Benzoguanamine SCHEMBL21351508 | 0.75 | TPH1 (0.71) | TPH1 | |
| SCHEMBL20274801 | 0.75 | TPH1 (0.70) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058598-A1 | METHODS OF PREVENTING AND TREATING HYPERLIPIDEMIA OR ATHEROSCLEROSIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-05-03 | — | — | WO | disclosed |