Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545138 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL3982628 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL30660078 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL28559448 | 0.87 | FFAR1 (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL29169639 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL6307695 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL9586451 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL2927336 | 0.79 | BDKRB1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDCRHBP | |
| SCHEMBL9587439 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL9587150 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272325-C | Prepn of 1-((2-cyanobiphenyl-4-radical)methyl)-2-ethoxylbenzimidazole-7- ethyl formate as candixatan ester intermediate | TIANJIN INST OF PHARMACOLOGY (CN) | 2006-08-30 | — | — | CN | disclosed |
| CN-1058966-C | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1048486-C | Benzimidazole derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1147515-A | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-16 | — | — | CN | disclosed |
| CN-1055927-A | Benzimidazole derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-11-06 | — | — | CN | disclosed |