Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334697 | 0.91 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL28559448 | 0.90 | FFAR1 (0.40) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL2927336 | 0.88 | BDKRB1 (0.49) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL3976380 | 0.80 | SLC6A3 (0.52) | ALDH1A1BDKRB1HSD17B10CFTR | |
| SCHEMBL30660078 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL3982628 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL28451153 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL9034499 | 0.78 | BDKRB1 (0.46) | ALDH1A1HPGDKDM4EBDKRB1HSD17B10 | |
| SCHEMBL27964478 | 0.78 | CD274 (0.40) | ALDH1A1HPGDKDM4ECRHBPCRHR2 | |
| SCHEMBL29169639 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943937-A | Synthesis method of triphenyl candesartan | 浙江金立源药业有限公司 | 2020-11-17 | — | — | CN | disclosed |
| EP-1863801-A2 | BENZIMIDAZOLE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107062-A2 | BENZIMIDAZOLE DERIVATIVE AND USE AS ANGIOTENSIN II ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-12 | — | — | WO | disclosed |
| CN-1058966-C | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1048486-C | Benzimidazole derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1147515-A | Producing process for crystal of 2-oxyethyl-1-[2'-(1H-tetrazole-5-radical)diphenyl-4-(methyl)benzimidazole-7-hydroxy acid 1-(cyclohexyloxy) ethyl ester | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-04-16 | — | — | CN | disclosed |
| CN-1055927-A | Benzimidazole derivatives, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-11-06 | — | — | CN | disclosed |