SCHEMBL27337089

SCHEMBL27337089

O=C(CO)N(C(=O)NO)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
KMT2A Q03164 4/20 0.44
NPC1 O15118 2/20 0.44
HTT P42858 2/20 0.44
RAB9A P51151 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
POLB P06746 1/20 0.44
HDAC6 Q9UBN7 5/20 0.40
HDAC8 Q9BY41 4/20 0.40
HDAC1 Q13547 4/20 0.40
HDAC3 O15379 2/20 0.40
HDAC2 Q92769 2/20 0.40
NCOR2 Q9Y618 2/20 0.40
HDAC4 P56524 1/20 0.40
HDAC10 Q969S8 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
PAX8 Q06710 2/20 0.39
GLA P06280 2/20 0.39
TP53 P04637 2/20 0.39
MTNR1A P48039 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27693818 0.84 ALDH1A1 (0.39) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL27713681 0.84 ALDH1A1 (0.39) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL28766984 0.84 ALDH1A1 (0.39) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL27786066 0.80 HSD17B10 (0.39) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL27434141 0.77 ALDH1A1 (0.42) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL7320641 0.76 GAA (0.42) ALDH1A1KMT2ANPC1HTTRAB9A
Hydrochloric Acid SCHEMBL10729162 0.73 NPSR1 (0.36) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL27528693 0.71 NPC1 (0.47) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL10521343 0.71 ALDH1A1 (0.65) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL1563099 0.71 NPSR1 (0.58) ALDH1A1KMT2ANPC1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1048524-C Process for producing D-alpha amino acid KANEGAFUCHI CHEMICAL IND (JP) 2000-01-19 CN claimed
CN-1187444-C Enzymes with deaminoformyl activity KANEGAFUCHI CHEMICAL IND (JP) 2005-02-02 CN disclosed
CN-1048524-C Process for producing D-alpha amino acid KANEGAFUCHI CHEMICAL IND (JP) 2000-01-19 CN disclosed
CN-1221793-A Enzyme with deaminizating formyl activity KANEGAFUCHI CHEMICAL IND (JP) 1999-07-07 CN disclosed
CN-1102672-A Process for producing D-alpha amino acid KANEGAFUCHI CHEMICAL IND (JP) 1995-05-17 CN disclosed