Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742879 | 0.85 | NPC1 (0.46) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL27807993 | 0.83 | GAA (0.45) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL27528690 | 0.79 | NPC1 (0.46) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL5146531 | 0.74 | LMNA (0.55) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL6647621 | 0.72 | LMNA (0.57) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL27337089 | 0.71 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL544272 | 0.71 | NPC1 (0.75) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL31232614 | 0.69 | NPC1 (0.56) | NPC1RAB9AALDH1A1NPSR1KMT2A | |
| SCHEMBL5144037 | 0.69 | NPC1 (0.71) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL15373060 | 0.69 | MEN1 (0.59) | NPC1RAB9AALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282502-C | Preparation method and application of magnetic carrier immobilized Raney-Ni catalyst | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2006-11-01 | — | — | CN | disclosed |
| CN-1597106-A | Preparation method and application of magnetic carrier immobilized Raney-Ni catalyst | UNIV NANJING POLYTECHNICAL (CN) | 2005-03-23 | — | — | CN | disclosed |