Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15667384 | 0.92 | ALDH1A1 (0.47) | GAAALDH1A1KMT2ANPSR1NPC1 | |
| SCHEMBL27434141 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2ANPSR1NPC1HTT | |
| SCHEMBL11648159 | 0.81 | CRHBP (0.46) | GAAALDH1A1KMT2ANPSR1NPC1 | |
| SCHEMBL11282246 | 0.79 | ADRA2C (0.51) | GAAALDH1A1KMT2ANPSR1NPC1 | |
| SCHEMBL27337089 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ANPSR1NPC1HTT | |
| SCHEMBL1561385 | 0.75 | ALDH1A1 (0.63) | GAAALDH1A1KMT2ANPSR1NPC1 | |
| SCHEMBL27675508 | 0.75 | GAA (0.45) | GAAALDH1A1KMT2ANPSR1NPC1 | |
| SCHEMBL27382574 | 0.75 | ALDH1A1 (0.47) | GAAALDH1A1KMT2APOLBGLA | |
| SCHEMBL9666974 | 0.75 | NPC1 (0.48) | ALDH1A1KMT2ANPC1HTTRAB9A | |
| SCHEMBL28766984 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KMT2ANPSR1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | disclosed |