Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160614 | 0.74 | SKP2 (0.47) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL12971475 | 0.73 | SKP2 (0.42) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL3668658 | 0.72 | NOS3 (0.31) | NOS2 | |
| SCHEMBL10342531 | 0.71 | SKP2 (0.57) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL27495210 | 0.71 | SKP2 (0.52) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL21675414 | 0.69 | NOS2 (0.33) | NOS2 | |
| SCHEMBL15556560 | 0.69 | SKP2 (0.50) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL27603659 | 0.69 | SKP2 (0.42) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL5185158 | 0.69 | SKP2 (0.41) | SKP2HTTNPC1HPGDMAPK1 | |
| SCHEMBL19228627 | 0.69 | HTT (0.43) | SKP2HTTNPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130161-A2 | NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | BIONECURE THERAPEUTICS INC (US) | 2024-06-20 | — | — | WO | disclosed |