SCHEMBL3668658

SCHEMBL3668658

CCc1c(C)c(N)cc(F)c1N

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP7 P55210 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27705440 0.78 ALDH1A1 (0.41) NOS3NOS2ALDH1A1CYP1A2ALOX15
Hydrochloric Acid SCHEMBL4663728 0.77 ALDH1A1 (0.40) NOS3NOS2ALDH1A1CYP1A2ALOX15
SCHEMBL150659 0.77 ALDH1A1 (0.41) NOS3NOS2ALDH1A1CYP1A2ALOX15
SCHEMBL3676570 0.75 ALDH1A1 (0.33) ALDH1A1CYP1A2ALOX15CASP7HIF1A
SCHEMBL3678294 0.74 TAAR1 (0.32) ALDH1A1
SCHEMBL28794153 0.73 ALDH1A1 (0.39) NOS3NOS2ALDH1A1CYP1A2ALOX15
SCHEMBL27337121 0.72 SKP2 (0.42) NOS2
SCHEMBL29229206 0.72 HTT (0.44) ALDH1A1CYP1A2
SCHEMBL9494017 0.71 TAAR1 (0.33)
SCHEMBL30490126 0.71 CA1 (0.36) CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed