Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876928 | 0.75 | NPC1 (0.44) | KMT2ASMN1; SMN2 | |
| SCHEMBL30578654 | 0.69 | TBXAS1 (0.44) | TBXAS1 | |
| SCHEMBL12391771 | 0.68 | TBXAS1 (0.49) | TBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4847586 | 0.66 | FPR2 (0.40) | — | |
| SCHEMBL8068830 | 0.66 | TERT (0.42) | TBXAS1 | |
| SCHEMBL3682800 | 0.65 | SMN1; SMN2 (0.56) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24306044 | 0.64 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL1414204 | 0.64 | TAAR1 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL16133628 | 0.64 | TERT (0.49) | TBXAS1ALDH1A1 | |
| SCHEMBL11290843 | 0.64 | TBXAS1 (0.34) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047085-A | The dipeptides of renin-inhibiting, its preparation method contains the medicament and the application thereof of these dipeptides | HOECHST AG (DE) | 1990-11-21 | — | — | CN | disclosed |