SCHEMBL27337668

SCHEMBL27337668

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NR1H4 Q96RI1 1/20 0.32
TSHR P16473 1/20 0.31
KIF11 P52732 1/20 0.30
S1PR1 P21453 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28050155 0.88 RXRB (0.32)
SCHEMBL27494089 0.84 PDCD1 (0.34) BRD4
SCHEMBL21403456 0.83 NR1H4 (0.31) BRD4CREBBPNR1H4
SCHEMBL29534184 0.83 NPC1 (0.31) NPC1LMNATP53RAB9ASMN1; SMN2
SCHEMBL28755323 0.83 BRD4 (0.32) BRD4CREBBPNPC1LMNATP53
SCHEMBL27663762 0.83 NPC1 (0.34) BRD4CREBBPNPC1LMNATP53
SCHEMBL8468224 0.82 PDCD1 (0.33) BRD4
Hydrochloric Acid SCHEMBL5169310 0.81 PDCD1 (0.33) BRD4
SCHEMBL2235436 0.80 BRD4 (0.32) BRD4CREBBPNPC1LMNATP53
SCHEMBL2234772 0.80 BRD4 (0.32) BRD4CREBBPNPC1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209126-A1 HYBRID SUPPORTED METALLOCENE CATALYST AND METHOD FOR PREPARING POLYPROPYLENE USING THE SAME LG CHEM, LTD. (KR) 2024-06-27 US disclosed