SCHEMBL2733837

SCHEMBL2733837

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN(C)C)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.72
LPAR3 Q9UBY5 7/20 0.69
LPAR1 Q92633 4/20 0.69
ENPP2 Q13822 5/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
LPAR2 Q9HBW0 2/20 0.63
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.61
SMPD1 P17405 1/20 0.61
SELP P16109 1/20 0.58
PLCG2 P16885 1/20 0.57
NR5A2 O00482 1/20 0.56
NR5A1 Q13285 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14878462 1.00 FABP3 (0.72) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL2734331 1.00 FABP3 (0.72) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL30950728 1.00 FABP3 (0.72) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL13638356 1.00 FABP3 (0.72) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL14758291 0.95 FABP3 (0.66) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL23188409 0.94 SELP (0.68) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL23225813 0.94 SELP (0.68) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL23188412 0.94 SELP (0.68) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL15336893 0.94 SELP (0.68) FABP3LPAR3LPAR1ENPP2SMN1; SMN2
SCHEMBL14887282 0.94 SELP (0.68) FABP3LPAR3LPAR1ENPP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056467-A1 POLYPHOSPHOESTER STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO claimed
WO-2025056466-A1 POLYVINYLPYRROLIDONE STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO claimed
WO-2025049579-A1 INTRANASAL FORMULATION FOR PULMONARY DELIVERY OF NANOPARTICLES, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-06 WO claimed
CN-122055141-A Polyvinylpyrrolidone stabilizer, composition, use and preparation method thereof 环球生命科学解决方案加拿大有限公司 2026-05-15 CN disclosed
WO-2025056467-A1 POLYPHOSPHOESTER STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO disclosed
WO-2025056466-A1 POLYVINYLPYRROLIDONE STABILIZING AGENTS, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-20 WO disclosed
WO-2025049579-A1 INTRANASAL FORMULATION FOR PULMONARY DELIVERY OF NANOPARTICLES, COMPOSITIONS, USES, AND MANUFACTURING METHODS THEREOF GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC (CA) 2025-03-06 WO disclosed
US-20170312375-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND LANTHEUS MEDICAL IMAGING, INC. (US) 2017-11-02 US disclosed
US-9545457-B2 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend LANTHEUS MEDICAL IMAGING, INC. (US) 2017-01-17 US disclosed
US-20150023880-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND LANTHEUS MEDICAL IMAGING, INC. (US) 2015-01-22 US disclosed
US-8747892-B2 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend LANTHEUS MEDICAL IMAGING, INC. (US) 2014-06-10 US disclosed
US-8658205-B2 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend LANTHEUS MEDICAL IMAGING, INC. (US) 2014-02-25 US disclosed
US-20130281510-A1 siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis KUMAMOTO UNIVERSITY (JP) 2013-10-24 US disclosed
US-7906147-B2 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography NANOPROBES, INC. (US) 2011-03-15 US disclosed
US-20080089836-A1 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography NANOPROBES, INC. (US) 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170312375-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND PHOSPHO1, PLTP, APOB FABP3 21/4885LPAR3 40/4885LPAR1 43/4885
US-20080089836-A1 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography TFRC, FABP1, SCARB1 FABP3 5/4885LPAR3 322/4885LPAR1 232/4885
US-20150023880-A1 PREPARATION OF A LIPID BLEND AND A PHOSPHOLIPID SUSPENSION CONTAINING THE LIPID BLEND PHOSPHO1, PLTP, APOB FABP3 21/4885LPAR3 40/4885LPAR1 43/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.