Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 7/20 | 0.33 |
| ▸ | SCD | O00767 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 5/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CPS1 | P31327 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468829 | 0.89 | SCD5 (0.34) | SCD5SCDBACE1CPT2CPT1A | |
| SCHEMBL2727474 | 0.83 | BACE1 (0.48) | SCD5SCDBACE1CPT2CPT1A | |
| SCHEMBL6465415 | 0.83 | BACE1 (0.48) | SCD5SCDBACE1CPT2CPT1A | |
| SCHEMBL2727473 | 0.83 | BACE1 (0.48) | SCD5SCDBACE1CPT2CPT1A | |
| SCHEMBL2725547 | 0.81 | BACE1 (0.39) | SCD5SCDBACE1CPT2CPT1A | |
| SCHEMBL2734099 | 0.81 | TRPV1 (0.34) | CPT2CPT1ATRPV1CPS1HCRTR1 | |
| SCHEMBL6468229 | 0.79 | BACE1 (0.37) | BACE1CPT2CPT1ACPT1BTRPV1 | |
| SCHEMBL6466217 | 0.78 | BACE1 (0.36) | BACE1CPT2CPT1ACPT1BTRPV1 | |
| SCHEMBL2728770 | 0.78 | BACE1 (0.36) | BACE1CPT2CPT1ACPT1BTRPV1 | |
| SCHEMBL2731978 | 0.76 | TRPV1 (0.34) | BACE1CPT2CPT1ACPT1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |