Naphthalene

Naphthalene

SCHEMBL27339031

CCCO.c1ccc2ccccc2c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.50
ALOX12 P18054 1/20 0.50
CYP1A2 P05177 2/20 0.44
TDP1 Q9NUW8 2/20 0.39
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ATM Q13315 2/20 0.38
HTT P42858 1/20 0.38
PPARG P37231 2/20 0.37
PPARA Q07869 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
NPC1 O15118 2/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
UGT2B7 P16662 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28227167 0.97 CYP2A6 (0.47) CYP2A6ALOX12CYP1A2TDP1RAB9A
Naphthalene SCHEMBL216220 0.87 CYP2A6 (0.57) CYP2A6ALOX12CYP1A2TDP1RAB9A
Naphthalene SCHEMBL27493313 0.86 ALDH1A1 (0.58) CYP2A6ALOX12CYP1A2RAB9AMEN1
Naphthalene SCHEMBL1080458 0.83 CYP2A6 (0.61) CYP2A6ALOX12CYP1A2TDP1TSHR
Naphthalene SCHEMBL1538234 0.83 CYP2A6 (0.61) CYP2A6ALOX12CYP1A2TDP1RAB9A
Naphthalene SCHEMBL15537489 0.82 LMNA (0.62) RAB9AMEN1KMT2AHTTTSHR
Decanol SCHEMBL27731676 0.82 LMNA (0.62) RAB9AMEN1KMT2AHTTTSHR
Nonanol SCHEMBL29217536 0.82 LMNA (0.62) RAB9AMEN1KMT2AHTTTSHR
Pyrene SCHEMBL29078946 0.80 ALDH1A1 (0.58) CYP1A2TDP1MEN1KMT2AATM
Naphthalene SCHEMBL11774251 0.79 CYP2A6 (0.67) CYP2A6ALOX12CYP1A2TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436851-A Preparation method of N, N-dimethylbenzylamine and derivative thereof 常州大学 2022-05-06 CN claimed
CN-101574646-B Lipase bonded stationary phase and preparation method and use thereof UNIV CHINA AGRICULTURAL 2011-07-20 CN claimed
CN-101574646-A Lipase bonded stationary phase and preparation method and use thereof UNIV CHINA AGRICULTURAL (CN) 2009-11-11 CN claimed
CN-1045391-C Oral delivery system BIOTECH AUSTRALIA PTY LTD (AU) 1999-10-06 CN claimed
CN-86107590-A Oral administration system 1987-05-20 CN claimed
CN-107245024-B A kind of preparation method of the third benzene and its derivative of 1- chlorine 西南化工研究设计院有限公司 2019-10-25 CN disclosed
CN-107245024-A A kind of preparation method of the benzene and its derivative of 1 chlorine third 西南化工研究设计院有限公司 2017-10-13 CN disclosed
CN-101574646-B Lipase bonded stationary phase and preparation method and use thereof UNIV CHINA AGRICULTURAL 2011-07-20 CN disclosed
CN-101574646-A Lipase bonded stationary phase and preparation method and use thereof UNIV CHINA AGRICULTURAL (CN) 2009-11-11 CN disclosed
CN-1274839-C Process for the preparation of enantiomerically enriched esters and alcohols DSM NV (NL) 2006-09-13 CN disclosed
CN-1430677-A Process for the preparation of enantiomerically enriched esters and alcohols DSM NV (NL) 2003-07-16 CN disclosed