Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598545 | 0.96 | TSHR (0.55) | TSHRHPGDTHRBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2733907 | 0.95 | TSHR (0.53) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL10483610 | 0.93 | TSHR (0.52) | TSHRHPGDTHRBALDH1A1TP53 | |
| Methylsulfanylmethane SCHEMBL10483613 | 0.93 | TSHR (0.52) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL31509595 | 0.87 | TSHR (0.56) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27553632 | 0.86 | TSHR (0.61) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL11024591 | 0.85 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL14335996 | 0.85 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL2470945 | 0.84 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL5451161 | 0.84 | TSHR (0.59) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140004200-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-01-02 | — | — | US | disclosed |
| US-8193267-B2 | Polymer compositions with bioactive agent, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-06-05 | — | — | US | disclosed |
| EP-1689456-B1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20100233273-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2010-09-16 | — | — | US | disclosed |
| US-7745509-B2 | Polymer compositions with bioactive agent, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-06-29 | — | — | US | disclosed |
| EP-1689456-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | 3M Innovative Properties Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056070-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20050124724-A1 | Polymer compositions with bioactive agent, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-09 | — | — | US | disclosed |
| US-20040180093-A1 | Polymer compositions with bioactive agent, medical articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140004200-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | ZRANB2, PUF60, BMP2 | TSHR 4202/4885HPGD 2425/4885THRB 4510/4885 |
| US-20100233273-A1 | POLYMER COMPOSITIONS WITH BIOACTIVE AGENT, MEDICAL ARTICLES, AND METHODS | BMP2, ZRANB2, PUF60 | TSHR 4415/4885HPGD 2396/4885THRB 4357/4885 |
| US-20040180093-A1 | Polymer compositions with bioactive agent, medical articles, and methods | ZRANB2, PUF60, BMP2 | TSHR 4202/4885HPGD 2425/4885THRB 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.