Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670079 | 1.00 | ATM (0.42) | ATMTNFPDK2BACE1KCNH2 | |
| SCHEMBL16677154 | 0.96 | ATM (0.38) | ATMPDK2BACE1KCNH2CYP1B1 | |
| SCHEMBL2734065 | 0.92 | ATM (0.43) | ATMTNFPDK2BACE1KCNH2 | |
| SCHEMBL16670006 | 0.87 | ALDH1A1 (0.41) | ATMTNFALDH1A1TSHRMAPK1 | |
| SCHEMBL16658473 | 0.85 | CYP11B1 (0.47) | TNFPDK2ALDH1A1TSHRMAPK1 | |
| SCHEMBL16859291 | 0.84 | ALDH1A1 (0.44) | ATMTNFBACE1ALDH1A1TSHR | |
| SCHEMBL16658474 | 0.82 | IMPDH2 (0.42) | TNFALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL18079812 | 0.81 | BACE1 (0.36) | ATMBACE1KCNH2KAT6APRKDC | |
| SCHEMBL2158220 | 0.81 | ALDH1A1 (0.47) | ATMTNFBACE1ALDH1A1TSHR | |
| SCHEMBL251545 | 0.81 | CYP11B1 (0.48) | TNFPDK2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | NR0B1, AR, NR0B2 | ATM 2439/4885TNF 4721/4885PDK2 3733/4885 |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | AR, CCND3, ESRRA | ATM 1086/4885TNF 4725/4885PDK2 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.