Chlorobenzene

Chlorobenzene

SCHEMBL27340652

CCOC(=O)C(C)C.Clc1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.50
NPC1 O15118 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MMP8 P22894 2/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
LMNA P02545 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 1/20 0.44
TNF P01375 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HPGD P15428 1/20 0.44
ALOX12 P18054 1/20 0.44
CCR6 P51684 1/20 0.44
RUNX1 Q01196 1/20 0.44
CBFB Q13951 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL7044583 0.85 PIN1 (0.53) PIN1NPC1MEN1KMT2AMMP8
Benzene SCHEMBL28153331 0.84 PIN1 (0.48) PIN1NPC1MEN1KMT2AMMP8
Chlorobenzene SCHEMBL11711196 0.84 MEN1 (0.56) PIN1NPC1MEN1KMT2AMMP8
Phenol SCHEMBL5006868 0.83 PIN1 (0.51) PIN1NPC1MEN1KMT2AMMP8
Benzene SCHEMBL27512416 0.82 PIN1 (0.47) PIN1NPC1MEN1KMT2AMMP8
Phenol SCHEMBL28225163 0.81 PIN1 (0.50) PIN1NPC1MEN1KMT2AMMP8
Chlorobenzene SCHEMBL16616568 0.81 ALDH1A1 (0.56) PIN1NPC1MEN1KMT2ATSHR
Chlorobenzene SCHEMBL15562499 0.81 ALDH1A1 (0.56) PIN1NPC1MEN1KMT2ATSHR
Chlorobenzene SCHEMBL18834102 0.81 ALDH1A1 (0.56) PIN1NPC1MEN1KMT2ATSHR
Ethyl Propionate SCHEMBL27547003 0.79 MEN1 (0.49) PIN1MEN1KMT2ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1044458-A Produce PTS \" anticancer spirit \" processing method NANCHANG GROUND FORCE COLLEGE (CN) 1990-08-08 CN disclosed