Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28153331 | 0.87 | PIN1 (0.48) | PIN1MEN1KMT2ANPC1MMP8 | |
| Phenol SCHEMBL5006868 | 0.86 | PIN1 (0.51) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL8038714 | 0.86 | PIN1 (0.51) | PIN1MEN1KMT2ANPC1MMP8 | |
| Benzene SCHEMBL27512416 | 0.85 | PIN1 (0.47) | PIN1MEN1KMT2ANPC1MMP8 | |
| Phenol SCHEMBL28225163 | 0.85 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| Chlorobenzene SCHEMBL27340652 | 0.85 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL29729061 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2ANPC1TSHRTDP1 | |
| Toluene SCHEMBL10334200 | 0.85 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL11773131 | 0.85 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| Toluene SCHEMBL28151256 | 0.82 | PIN1 (0.51) | PIN1MEN1KMT2ANPC1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274958-B | Method for preparing amide compound through catalysis of ligand-assisted zirconium oxychloride | UNIV XI AN SHIYOU | 2014-09-03 | — | — | CN | disclosed |
| CN-103274958-A | Method for preparing amide compound through catalysis of ligand-assisted zirconium oxychloride | UNIV XI AN SHIYOU | 2013-09-04 | — | — | CN | disclosed |
| EP-0956286-B1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6147217-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0956286-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5925761-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 1999-07-20 | — | — | US | disclosed |
| WO-1998033789-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1998-08-06 | — | — | WO | disclosed |