Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465900 | 0.75 | CHRM3 (0.47) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL5469826 | 0.74 | DRD2 (0.73) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL948505 | 0.74 | DRD2 (0.60) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL11098055 | 0.73 | DRD2 (0.58) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL5473682 | 0.72 | DRD2 (0.54) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL6611458 | 0.71 | DRD2 (0.65) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL7225414 | 0.71 | DRD2 (0.52) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14784803 | 0.70 | DRD2 (0.63) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9870657 | 0.70 | KMT2A (0.55) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL13517233 | 0.68 | SIGMAR1 (0.46) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060772-C | New Indole, Indazole and benzisoxazole compounds, their process of preparation and pharmaceutical compositions which contain them | ADIR (FR) | 2001-01-17 | — | — | CN | disclosed |
| CN-1143642-A | New indole, indazole and benzisoxazole compounds, their process of preparation and pharmaceutical compositions which contain them | ADIR (FR) | 1997-02-26 | — | — | CN | disclosed |