Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27341843 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL27341841 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL27341846 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL23252417 | 0.93 | ALDH1A1 (0.46) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL22043107 | 0.93 | ALDH1A1 (0.46) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL22356678 | 0.89 | ALDH1A1 (0.44) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL20273228 | 0.89 | ALDH1A1 (0.44) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL24326401 | 0.88 | HSD17B10 (0.43) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20281885 | 0.86 | HSD17B10 (0.46) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 | |
| SCHEMBL12524284 | 0.86 | HSD17B10 (0.46) | HSD17B10ALDH1A1SMN1; SMN2NR1H2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | CBS, MSR1, P4HB | HSD17B10 248/4885ALDH1A1 245/4885SMN1; SMN2 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.