SCHEMBL273440

SCHEMBL273440

CSCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
CASP1 P29466 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA2 P00918 1/20 0.48
TAAR1 Q96RJ0 3/20 0.48
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP2A6 P11509 1/20 0.48
HTR2A P28223 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
NOS1 P29475 1/20 0.46
TP53 P04637 1/20 0.46
IDO1 P14902 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687602 0.87 CA2 (0.53) CA2HTR2ANOS1AOC3MAOA
SCHEMBL1145863 0.85 MAOA (0.52) CA2MAOAMAOB
SCHEMBL12040636 0.84 SIGMAR1 (0.53) MAOAMAOB
SCHEMBL31500399 0.84 SIGMAR1 (0.53) MAOAMAOB
SCHEMBL12040614 0.84 SIGMAR1 (0.53) MAOAMAOB
SCHEMBL6690395 0.80 CYP1A2 (0.54) ALDH1A1CYP1A2CYP2D6CYP2C19HPGD
SCHEMBL10664294 0.79 CYP1A2 (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19HPGD
SCHEMBL14346666 0.79 CYP1A2 (0.52) ALDH1A1CYP1A2ALOX15TAAR1TDP1
SCHEMBL15959908 0.79 TAAR1 (0.52) ALDH1A1CYP2D6CA2TAAR1ATM
Phenethylamine SCHEMBL11431518 0.79 HTR2A (0.61) CYP1A2CYP2D6CYP2C19TAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947609-A Method for preparing 2, 2-dibromoacetophenone by C-S bond cleavage 常州大学 2023-10-27 CN claimed
US-6627656-B2 Antagonists of the pain and inflammatory effects of E-type prostaglandins administered alone or in combination with analgesics, antipyretics, NSAIDs, antitussives, decongestants etc MERCK FROSST CANADA LTD. (CA) 2003-09-30 US claimed
EP-1278734-A2 METHOD OF TREATMENT USING PHENYL AND BIARYL DERIVATIVES AS PROSTAGLANDIN E INHIBITORS AND COMPOUNDS USEFUL THEREFORE Merck Frosst Canada & Co. (CA) 2003-01-29 EP claimed
WO-2001081312-A2 METHOD OF TREATMENT USING PHENYL AND BIARYL DERIVATIVES AS PROSTAGLANDIN E INHIBITORS AND COMPOUNDS USEFUL THEREFORE MERCK FROSST CANADA & CO. (CA) 2001-11-01 WO claimed
US-5861428-A ALLEVIATION OF OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISEASE, CORNEAL ULCERATION, PROTEINURIA, ANEURYSMAL AORTIC DISEASE, DYSTROPHOBIC EPIDERMOLYSIS BULLOSA, INFLAMMATION, OSTEOPENIAS, TEMPERO BAYER CORPORATION (US) 1999-01-19 US claimed
US-4839352-A ANTIBIOTICS MERCK & CO., INC. (US) 1989-06-13 US claimed
US-4818749-A Carboxyalkyl dipeptides and medical use thereof in treating hypertension and congestive heart failure SCHERING CORPORATION (US) 1989-04-04 US claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
EP-4683503-A1 A NON-LETHAL USE AND METHOD FOR HERD PROTECTION fenaco Genossenschaft (CH) 2026-01-28 EP disclosed
CN-119899127-A Organic electrolyte used by matching (poly) dicyclopentadiene and carbon fiber surface treatment method 吉林大学 2025-04-29 CN disclosed
WO-2024194147-A1 A NON-LETHAL USE AND METHOD FOR HERD PROTECTION TIBIO SAGL (CH) 2024-09-26 WO disclosed
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2023215790-A1 CO-DELIVERY OF INHIBITORY NUCLEIC ACIDS AND GENOME EDITORS FOR TUMOR THERAPY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-11-09 WO disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-4086423-A CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND MERCK & CO., INC. (US) 1978-04-25 US disclosed
US-4071529-A Derivatives of 6-aminopenicillanic acid MERCK & CO., INC. (US) 1978-01-31 US disclosed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US disclosed
US-4035359-A 6α, β-Substituted penicillin derivatives MERCK & CO., INC. (US) 1977-07-12 US disclosed
US-4032521-A ANTIBIOTICS MERCK & CO., INC. (US) 1977-06-28 US disclosed
US-3947413-A ANTIBIOTICS MERCK & CO., INC. (US) 1976-03-30 US disclosed