Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461726 | 0.86 | KDM4E (0.46) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL27344301 | 0.85 | MAPK1 (0.42) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL27344098 | 0.83 | KDM4E (0.44) | KDM4ERAB9ANPC1KMT2APTGES | |
| SCHEMBL27344209 | 0.80 | RAB9A (0.45) | KDM4ERAB9ANPC1KMT2APTGES | |
| SCHEMBL27348584 | 0.80 | KDM4E (0.43) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL30702700 | 0.80 | KDM4E (0.43) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL30702710 | 0.79 | HTT (0.42) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL30702708 | 0.79 | HTT (0.42) | KDM4ERAB9ANPC1KMT2APOLB | |
| SCHEMBL27347623 | 0.79 | KDM4E (0.43) | KDM4ERAB9APTGESPOLBCDK2 | |
| SCHEMBL27344211 | 0.78 | ROCK2 (0.45) | KDM4ERAB9ANPC1POLBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |