Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344209 | 0.91 | RAB9A (0.45) | ROCK2ROCK1CDK2FLT3CCNA1 | |
| SCHEMBL30702704 | 0.86 | SMN1; SMN2 (0.44) | CDK2FLT3CCNA1POLBGAA | |
| SCHEMBL27347623 | 0.85 | KDM4E (0.43) | ROCK2ROCK1CDK2FLT3CCNA1 | |
| SCHEMBL27344320 | 0.83 | MCL1 (0.49) | ROCK2ROCK1POLBGAALMNA | |
| SCHEMBL27344298 | 0.82 | CDK2 (0.43) | ROCK2ROCK1CDK2FLT3CCNA1 | |
| SCHEMBL27348988 | 0.81 | ROCK2 (0.42) | ROCK2ROCK1CDK2FLT3CCNA1 | |
| SCHEMBL27344318 | 0.81 | KDM4E (0.49) | ROCK2ROCK1POLBGAALMNA | |
| SCHEMBL27344324 | 0.81 | KDM4E (0.56) | CDK2POLBGAALMNAHTT | |
| SCHEMBL34461726 | 0.80 | KDM4E (0.46) | CDK2FLT3CCNA1POLBGAA | |
| SCHEMBL27344207 | 0.79 | POLB (0.50) | ROCK2ROCK1CDK2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |