Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073208 | 0.86 | MAPT (0.65) | ALDH1A1HPGDKDM4EGFERMAPT | |
| SCHEMBL3373937 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL1136836 | 0.86 | KDM4E (0.66) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| SCHEMBL12608909 | 0.84 | GFER (0.62) | ALDH1A1HPGDKDM4EGFERMAPT | |
| SCHEMBL5017463 | 0.83 | LMNA (0.61) | ALDH1A1HPGDKDM4EMAPTTP53 | |
| Fenclozic Acid SCHEMBL27104 | 0.82 | LMNA (0.73) | ALDH1A1HPGDKDM4EGFERMAPT | |
| SCHEMBL3455040 | 0.81 | GFER (0.62) | ALDH1A1HPGDKDM4EGFERMAPT | |
| SCHEMBL8424253 | 0.81 | TP53 (0.60) | ALDH1A1HPGDKDM4EGFERMAPT | |
| SCHEMBL8240059 | 0.81 | SHMT1 (0.60) | ALDH1A1KDM4EGFERMAPTTHRB | |
| SCHEMBL5463617 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048386-A | Novel thiazole base alkoxy acrylic ester, they the preparation method, do the purposes of mycocide and prepare the intermediate of this compounds | ROUSSEL UCLAF (FR) | 1991-01-09 | — | — | CN | disclosed |