Ethylene

Ethylene

SCHEMBL27344274

C=C.O=C(O)c1csc(C(F)(F)F)n1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
PTGER1 P34995 7/20 0.41
LDHA P00338 3/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287556 0.96 KDM4E (0.47) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL578096 0.94 KDM4E (0.46) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL27830260 0.82 ALDH1A1 (0.35) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL27344272 0.82 ALDH1A1 (0.34) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL9568954 0.81 L3MBTL1 (0.42) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
Trifluoroacetic Acid SCHEMBL27830221 0.80 KDM4E (0.35) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL6844961 0.79 CBLB (0.35) KDM4EALDH1A1GAASMN1; SMN2LDHA
SCHEMBL15356473 0.79 KDM1A (0.41) KDM4EALDH1A1GAASMN1; SMN2L3MBTL1
SCHEMBL3262633 0.79 HTR2B (0.44) KDM4EALDH1A1GAASMN1; SMN2
Lithium Ion SCHEMBL578095 0.78 PTGER1 (0.36) KDM4EALDH1A1GAASMN1; SMN2PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1048386-A Novel thiazole base alkoxy acrylic ester, they the preparation method, do the purposes of mycocide and prepare the intermediate of this compounds ROUSSEL UCLAF (FR) 1991-01-09 CN disclosed