Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830260 | 0.84 | ALDH1A1 (0.35) | LMNAALDH1A1NPSR1GAAMAPT | |
| SCHEMBL287556 | 0.82 | KDM4E (0.47) | ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL457405 | 0.81 | HTR2B (0.44) | HTR2BKMT2ACYP2C19ACHECYP2C9 | |
| SCHEMBL578096 | 0.81 | KDM4E (0.46) | ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL15356473 | 0.81 | KDM1A (0.41) | ALDH1A1GAAMAPTHTTKDM4E | |
| SCHEMBL6844961 | 0.81 | CBLB (0.35) | LMNAALDH1A1NPSR1GAAMAPT | |
| SCHEMBL14844543 | 0.80 | ALDH1A1 (0.53) | LMNAALDH1A1NPSR1GAAMAPT | |
| Ethylene SCHEMBL27344274 | 0.79 | KDM4E (0.44) | ALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL8880276 | 0.78 | RAF1 (0.33) | LMNAALDH1A1NPSR1GAAMAPT | |
| Trifluoroacetic Acid SCHEMBL27830221 | 0.78 | KDM4E (0.35) | LMNAALDH1A1GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | claimed |
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-112299938-B | Method for preparing amine compound by reducing amide compound | 中国科学院兰州化学物理研究所 | 2021-12-28 | — | — | CN | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| CN-112299938-A | Method for preparing amine compound by reducing amide compound | 中国科学院兰州化学物理研究所 | 2021-02-02 | — | — | CN | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2018-10-25 | — | — | US | disclosed |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-27 | — | — | US | disclosed |
| US-10000482-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-9637491-B2 | Pyrazolo[4,3-D]pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-05-02 | — | — | US | disclosed |
| US-20150266882-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150259340-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| WO-2014060112-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2014060113-A1 | NOVEL KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | HTR2B 1705/4885KMT2A 2845/4885CYP2C19 451/4885 |
| US-20150259340-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | HTR2B 1922/4885KMT2A 921/4885CYP2C19 2941/4885 |
| US-20150266882-A1 | PYRAZOLO[4,3-D]PYRIMIDINES AS KINASE INHIBITORS | LRRK2, MYLK2, MYLK | HTR2B 1915/4885KMT2A 1345/4885CYP2C19 1846/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | HTR2B 1705/4885KMT2A 2845/4885CYP2C19 451/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | HTR2B 1705/4885KMT2A 2845/4885CYP2C19 451/4885 |
| US-20180305356-A1 | NOVEL KINASE INHIBITORS | LRRK2, MYLK2, MYLK | HTR2B 1922/4885KMT2A 921/4885CYP2C19 2941/4885 |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | HTR2B 1705/4885KMT2A 2845/4885CYP2C19 451/4885 |
| US-10000482-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | HTR2B 1659/4885KMT2A 929/4885CYP2C19 2888/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | HTR2B 1659/4885KMT2A 929/4885CYP2C19 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.