Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344320 | 0.92 | MCL1 (0.49) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL27348988 | 0.85 | ROCK2 (0.42) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL27344318 | 0.85 | KDM4E (0.49) | KDM4EMAPTGAAHTTPOLB | |
| SCHEMBL27344298 | 0.84 | CDK2 (0.43) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL27344207 | 0.83 | POLB (0.50) | KDM4EGAAPOLBEGFRCDK2 | |
| SCHEMBL30702708 | 0.82 | HTT (0.42) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL30702710 | 0.82 | HTT (0.42) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL27347554 | 0.82 | GAA (0.48) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL27344204 | 0.81 | ROCK2 (0.42) | KDM4EHSD17B10MAPTGAAALOX15 | |
| SCHEMBL30702704 | 0.81 | SMN1; SMN2 (0.44) | KDM4EHSD17B10MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |