Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344324 | 0.92 | KDM4E (0.56) | MCL1GAAKDM4EHSD17B10HTT | |
| SCHEMBL27344318 | 0.91 | KDM4E (0.49) | MCL1GAAKDM4EHTTMAPT | |
| SCHEMBL27348988 | 0.91 | ROCK2 (0.42) | MCL1GAAKDM4EHSD17B10HTT | |
| SCHEMBL27344207 | 0.88 | POLB (0.50) | MCL1GAAKDM4EROCK2ROCK1 | |
| SCHEMBL27347554 | 0.87 | GAA (0.48) | MCL1GAAKDM4EMAPTROCK2 | |
| SCHEMBL27344204 | 0.87 | ROCK2 (0.42) | MCL1GAAKDM4EHSD17B10HTT | |
| SCHEMBL27344298 | 0.86 | CDK2 (0.43) | GAAKDM4EHSD17B10HTTMAPT | |
| SCHEMBL27344211 | 0.83 | ROCK2 (0.45) | GAAKDM4EHTTMAPTROCK2 | |
| SCHEMBL30702710 | 0.82 | HTT (0.42) | GAAKDM4EHSD17B10HTTMAPT | |
| SCHEMBL30702708 | 0.82 | HTT (0.42) | GAAKDM4EHSD17B10HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |