Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344320 | 0.88 | MCL1 (0.49) | POLBMCL1GAAKDM4EROCK2 | |
| SCHEMBL27348988 | 0.86 | ROCK2 (0.42) | POLBMCL1GAACDK2KDM4E | |
| SCHEMBL27344318 | 0.86 | KDM4E (0.49) | POLBMCL1GAAKDM4EROCK2 | |
| SCHEMBL27347554 | 0.83 | GAA (0.48) | POLBMCL1GAAKDM4EROCK2 | |
| SCHEMBL27344204 | 0.83 | ROCK2 (0.42) | POLBMCL1GAACDK2KDM4E | |
| SCHEMBL27344324 | 0.83 | KDM4E (0.56) | POLBMCL1GAAEGFRCDK2 | |
| SCHEMBL27344298 | 0.82 | CDK2 (0.43) | POLBGAAEGFRCDK2KDM4E | |
| SCHEMBL27344211 | 0.79 | ROCK2 (0.45) | POLBGAACDK2KDM4EROCK2 | |
| SCHEMBL27344209 | 0.78 | RAB9A (0.45) | POLBPTGESGAACDK2KDM4E | |
| SCHEMBL30702704 | 0.77 | SMN1; SMN2 (0.44) | POLBL3MBTL1GAAEGFRCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |