Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403165 | 0.85 | ALOX5 (0.41) | ABL1CA12CA9SNCA | |
| SCHEMBL18448706 | 0.82 | ACE2 (0.45) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL28404933 | 0.82 | ABL1 (0.43) | ABL1CA12CA9SNCA | |
| SCHEMBL27344614 | 0.81 | KIF11 (0.41) | ACE2KIF11ABL1CA12CA9 | |
| SCHEMBL27344609 | 0.78 | ACE2 (0.46) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL30811571 | 0.78 | ACE2 (0.49) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL27344608 | 0.78 | ACE2 (0.46) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL27344291 | 0.78 | ACE2 (0.49) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL27344284 | 0.78 | ACE2 (0.49) | ACE2KIF11JUNNFKB1NFKB2 | |
| SCHEMBL27344606 | 0.78 | ACE2 (0.46) | ACE2KIF11JUNNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |