Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344798 | 0.83 | MAPT (0.51) | MAPTALDH1A1HPGDALOX5HTR7 | |
| SCHEMBL4859644 | 0.79 | ALOX5 (0.74) | MAPTALOX5HTR7HTR2BKDM4E | |
| SCHEMBL121074 | 0.77 | ALOX5 (0.55) | ALDH1A1HPGDALOX5KDM4EGAA | |
| SCHEMBL30530994 | 0.77 | ALOX5 (0.55) | ALDH1A1HPGDALOX5KDM4EGAA | |
| SCHEMBL31191628 | 0.77 | ALOX5 (0.55) | ALDH1A1HPGDALOX5KDM4EGAA | |
| SCHEMBL28571843 | 0.75 | ALOX5 (0.53) | ALDH1A1HPGDALOX5KDM4EGAA | |
| Hydrochloric Acid SCHEMBL31235549 | 0.75 | ALOX5 (0.53) | ALDH1A1HPGDALOX5HTR7HTR2B | |
| SCHEMBL30811542 | 0.75 | PDE3B (0.50) | MAPTALDH1A1KDM4EMEN1GAA | |
| SCHEMBL27344794 | 0.75 | PDE3B (0.50) | MAPTALDH1A1KDM4EMEN1GAA | |
| Nitric Acid SCHEMBL997582 | 0.73 | ALOX5 (0.47) | MAPTALDH1A1ALOX5HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |