Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344796 | 0.83 | MAPT (0.52) | MAPTALDH1A1HPGDALOX5KMT2A | |
| SCHEMBL22131480 | 0.80 | TDP1 (0.49) | MAPTALDH1A1ALOX5KMT2AMEN1 | |
| SCHEMBL4859644 | 0.78 | ALOX5 (0.74) | MAPTALOX5KMT2AMEN1GAA | |
| SCHEMBL22961244 | 0.77 | AHR (0.39) | MAPTALDH1A1HPGDALOX5KMT2A | |
| SCHEMBL22087145 | 0.76 | KMT2A (0.41) | MAPTALOX5KMT2AMEN1GAA | |
| SCHEMBL29531401 | 0.76 | ALOX5 (0.55) | MAPTALDH1A1HPGDALOX5KMT2A | |
| SCHEMBL303370 | 0.76 | ALOX5 (0.55) | MAPTALDH1A1HPGDALOX5KMT2A | |
| SCHEMBL30811606 | 0.76 | PDE3B (0.52) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL27344797 | 0.76 | PDE3B (0.52) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL27346280 | 0.75 | ALOX5 (0.34) | MAPTALDH1A1ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |