Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL27345180 | 1.00 | ACHE (0.72) | ACHEBCHE | |
| Maleic Acid SCHEMBL6989248 | 0.92 | ACHE (0.85) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6989253 | 0.92 | ACHE (0.85) | ACHEBCHE | |
| Maleic Acid SCHEMBL27339122 | 0.89 | ACHE (0.72) | ACHEBCHE | |
| Maleic Acid SCHEMBL27339121 | 0.89 | ACHE (0.72) | ACHEBCHE | |
| Maleic Acid SCHEMBL27352167 | 0.89 | ACHE (0.69) | ACHEBCHE | |
| Maleic Acid SCHEMBL27352164 | 0.89 | ACHE (0.69) | ACHEBCHE | |
| Maleic Acid SCHEMBL27341693 | 0.86 | ACHE (0.71) | ACHEBCHE | |
| Maleic Acid SCHEMBL27341695 | 0.86 | ACHE (0.71) | ACHEBCHE | |
| Fumaric Acid SCHEMBL9411335 | 0.84 | ACHE (0.72) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1044242-C | Heterocyclic-cyclic amine derivatives | PFIZER (US) | 1999-07-21 | — | — | CN | disclosed |
| CN-1065267-A | HETEROCYCLIC-CYCLIC AMINE DERIVATIVES | PFIZER (US) | 1992-10-14 | — | — | CN | disclosed |