Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969619 | 1.00 | ALDH1A1 (0.36) | ALDH1A1SIRT6NR1H2NR1H3MTNR1A | |
| SCHEMBL24320368 | 0.93 | ALDH1A1 (0.40) | ALDH1A1SIRT6OPRK1MAPTKDM4E | |
| SCHEMBL24319289 | 0.91 | ALDH1A1 (0.36) | ALDH1A1SIRT6NR1H2NR1H3MAPT | |
| SCHEMBL26969658 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MTNR1AMTNR1BNOTUMMAPT | |
| SCHEMBL27123984 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MTNR1AMTNR1BNOTUMMAPT | |
| SCHEMBL26648895 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SIRT6OPRK1MAPTKDM4E | |
| SCHEMBL27371699 | 0.83 | SIRT6 (0.38) | ALDH1A1SIRT6OPRK1MAPTKDM4E | |
| SCHEMBL27194259 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SIRT6KDM4ENPC1HPGD | |
| SCHEMBL30680830 | 0.81 | CHRM4 (0.42) | ALDH1A1NR1H2NR1H3NOTUMMAPT | |
| SCHEMBL27345252 | 0.81 | CHRM4 (0.42) | ALDH1A1NR1H2NR1H3NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245150-A1 | KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |