Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245611 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL27345361 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL30719517 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL25317014 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL6886969 | 0.80 | USP2 (0.65) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL27345345 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL30719479 | 0.78 | DHCR7 (0.65) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL27344746 | 0.78 | DHCR7 (0.65) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL27344646 | 0.78 | DHCR7 (0.65) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 | |
| SCHEMBL6880993 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2LMNAGAADHCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |