SCHEMBL2734568

SCHEMBL2734568

Cc1c(-c2cccnc2)c(-c2ccccc2)c2c(c1-c1ccccc1)-c1cccc3cccc-2c13

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.43
KDM4E B2RXH2 5/20 0.42
TNF P01375 1/20 0.42
CYP2A6 P11509 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
POLB P06746 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP11B1 P15538 6/20 0.41
CYP11B2 P19099 5/20 0.41
RAB9A P51151 2/20 0.41
TSHR P16473 2/20 0.41
AHR P35869 1/20 0.41
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734768 0.93 TNF (0.47) RXFP1KDM4ETNFCYP2A6ALDH1A1
SCHEMBL2733768 0.93 TNF (0.47) RXFP1KDM4ETNFCYP2A6ALDH1A1
SCHEMBL4669618 0.85 ALDH1A1 (0.45) KDM4EALDH1A1HPGDSMN1; SMN2POLB
SCHEMBL23075856 0.84 CYP11B1 (0.51) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL2734079 0.81 CYP11B1 (0.49) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL18058477 0.80 TNF (0.42) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL251545 0.80 CYP11B1 (0.48) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL12731986 0.78 KDM4E (0.46) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL16658470 0.78 CYP11B1 (0.48) KDM4ETNFCYP2A6ALDH1A1HPGD
SCHEMBL728324 0.78 ALDH1A1 (0.56) KDM4ETNFALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed