Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728324 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL2734568 | 0.85 | RXFP1 (0.43) | ALDH1A1HSD17B10TSHRMAPK1L3MBTL1 | |
| SCHEMBL30104096 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL30155046 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL503284 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL24190998 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL22147377 | 0.78 | MMP3 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL728300 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL13183873 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRMAPK1ATM | |
| SCHEMBL24067717 | 0.76 | HSD17B10 (0.54) | ALDH1A1HSD17B10TSHRMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673322-B1 | SYNTHESIS OF PHENYL-SUBSTITUTED FLUORANTHENES BY A DIESEL-ALDER REACTION AND THE USE THEREOF | BASF SE (DE) | 2008-04-16 | — | — | EP | disclosed |