Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345598 | 0.91 | LMNA (0.46) | EGFRLMNAHTTMEN1KMT2A | |
| SCHEMBL27345690 | 0.90 | MEN1 (0.46) | EGFRLMNAMEN1KMT2AMRGPRX4 | |
| SCHEMBL27345782 | 0.87 | EGFR (0.44) | EGFRLMNAHTTMRGPRX4NPC1 | |
| SCHEMBL27345687 | 0.85 | MRGPRX4 (0.52) | EGFRLMNAHTTMEN1KMT2A | |
| SCHEMBL27345772 | 0.85 | LMNA (0.46) | EGFRLMNAHTTMEN1KMT2A | |
| SCHEMBL27345601 | 0.85 | EGFR (0.48) | EGFRLMNAMEN1KMT2APOLB | |
| SCHEMBL1516719 | 0.81 | EGFR (0.48) | EGFRHTTMEN1KMT2ANPC1 | |
| SCHEMBL27345779 | 0.81 | EGFR (0.48) | EGFRLMNAHTTMEN1KMT2A | |
| SCHEMBL17129014 | 0.81 | EGFR (0.47) | EGFRMEN1KMT2AMRGPRX4NPC1 | |
| SCHEMBL23484499 | 0.80 | LPL (0.48) | EGFRLMNAHTTPOLBLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |