SCHEMBL2734582

SCHEMBL2734582

c1ccc(-c2c(-c3ccncc3)c(-c3ccncc3)c(-c3ccccc3)c3c2-c2cccc4c(-c5ccccc5)ccc-3c24)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.50
IMPDH2 P12268 4/20 0.47
MAPK1 P28482 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TNF P01375 1/20 0.47
NOTUM Q6P988 1/20 0.45
PIK3CA P42336 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
METAP2 P50579 1/20 0.40
MAPK14 Q16539 1/20 0.40
CYP17A1 P05093 1/20 0.40
CYP1A2 P05177 1/20 0.40
HTR6 P50406 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
AURKA O14965 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13145248 0.91 CYP11B1 (0.49) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL24067817 0.91 PIK3CD (0.43) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL3511045 0.89 METAP2 (0.43) MAPK1HSD17B10TNFALDH1A1HPGD
SCHEMBL26411623 0.88 MAPK14 (0.46) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL19167865 0.86 TNF (0.42) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL16484454 0.85 PIK3CA (0.40) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL4076119 0.84 ENPP1 (0.42) MAPK1HSD17B10TNFALDH1A1HPGD
SCHEMBL16484466 0.84 PIK3CA (0.39) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL16484562 0.83 TNF (0.39) PIK3CDIMPDH2MAPK1HSD17B10TNF
SCHEMBL16484461 0.83 IMPDH2 (0.43) PIK3CDIMPDH2MAPK1HSD17B10TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed