SCHEMBL3511045

SCHEMBL3511045

c1ccc(-c2c(-c3ccccc3)c(-c3ccccc3)c3c(c2-c2ccccc2)-c2cccc4c(-c5ccccc5)ccc-3c24)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.43
PARP1 P09874 1/20 0.42
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ENPP1 P22413 2/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
LIMK1 P53667 2/20 0.39
CLK4 Q9HAZ1 2/20 0.39
PLK4 O00444 1/20 0.39
MAPK9 P45984 1/20 0.39
AKT3 Q9Y243 1/20 0.39
TNF P01375 1/20 0.39
CDK4 P11802 2/20 0.38
CCND1 P24385 2/20 0.38
MAP4K4 O95819 1/20 0.38
CSF1R P07333 1/20 0.38
FGFR1 P11362 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076119 0.94 ENPP1 (0.42) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL2734582 0.89 PIK3CD (0.50) METAP2AKT3TNFFGFR1ALDH1A1
SCHEMBL21368234 0.89 CYP1A2 (0.45) METAP2PARP1KEAP1NFE2L2ENPP1
SCHEMBL12032255 0.87 ALDH1A1 (0.35) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL1008377 0.86 CA12 (0.37) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL76836 0.86 CA12 (0.37) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL4081786 0.86 CA12 (0.44) ENPP1TNFALDH1A1HSD17B10HPGD
SCHEMBL31107072 0.85 CRHBP (0.56) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL2033903 0.85 CRHBP (0.56) METAP2PARP1CRHBPCRHR2KEAP1
SCHEMBL11888000 0.84 ENPP1 (0.37) METAP2PARP1CRHBPCRHR2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9634256-B2 Electroluminescent devices including organic EIL layer GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-25 US claimed
US-20150311447-A1 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER GLOBAL OLED TECHNOLOGY LLC (US) 2015-10-29 US claimed
US-20100084647-A1 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER GLOBAL OLED TECHNOLOGY LLC 2010-04-08 US claimed
EP-2011178-A2 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC ELECTRON INJECTION LAYER EASTMAN KODAK COMPANY (US) 2009-01-07 EP claimed
WO-2007127063-A2 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER EASTMAN KODAK COMPANY (US) 2007-11-08 WO claimed
US-20070252516-A1 Electroluminescent devices including organic EIL layer EASTMAN KODAK COMPANY 2007-11-01 US claimed
US-9634256-B2 Electroluminescent devices including organic EIL layer GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-25 US disclosed
EP-2415095-B1 TANDEM WHITE OLED WITH EFFICIENT ELECTRON TRANSFER GLOBAL OLED TECHNOLOGY LLC (US) 2016-08-10 EP disclosed
US-20150311447-A1 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER GLOBAL OLED TECHNOLOGY LLC (US) 2015-10-29 US disclosed
US-9118020-B2 Electroluminescent devices including organic eil layer GLOBAL OLED TECHNOLOGY LLC (US) 2015-08-25 US disclosed
US-20100084647-A1 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER GLOBAL OLED TECHNOLOGY LLC 2010-04-08 US disclosed
EP-2011178-A2 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC ELECTRON INJECTION LAYER EASTMAN KODAK COMPANY (US) 2009-01-07 EP disclosed
WO-2007127063-A2 ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER EASTMAN KODAK COMPANY (US) 2007-11-08 WO disclosed
US-20070252516-A1 Electroluminescent devices including organic EIL layer EASTMAN KODAK COMPANY 2007-11-01 US disclosed