Flualamide

Flualamide

SCHEMBL2734613

C=CCOc1cc(C(F)(F)F)ccc1C(=O)NCCN(CC)CC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MCHR1 Q99705 15/20 0.58
▸ NPC1 O15118 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ SLC22A2 O15244 1/20 0.44
▸ SLC22A1 O15245 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ ACHE P22303 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flualamide SCHEMBL29804765 1.00 MCHR1 (0.58) MCHR1NPC1RAB9ASLC22A2SLC22A1
Alloclamide SCHEMBL872157 0.84 MCHR1 (0.53) MCHR1RAB9ASLC22A1ALDH1A1LMNA
Alloclamide SCHEMBL29730070 0.84 MCHR1 (0.53) MCHR1RAB9ASLC22A1ALDH1A1LMNA
Alloclamide SCHEMBL209095 0.83 MCHR1 (0.52) MCHR1RAB9ASLC22A1ALDH1A1LMNA
Alloclamide SCHEMBL27527103 0.82 MCHR1 (0.51) MCHR1RAB9ASLC22A1ALDH1A1LMNA
SCHEMBL6365174 0.81 LIG1 (0.60) MCHR1SLC22A2SLC22A1ALDH1A1LMNA
SCHEMBL20471847 0.77 CFTR (0.55) NPC1RAB9AALDH1A1LMNATSHR
SCHEMBL11787896 0.77 RAB9A (0.59) MCHR1RAB9AALDH1A1MAPK1
SCHEMBL15126164 0.76 ALDH1A1 (0.57) ALDH1A1TSHRCYP2C19
SCHEMBL20471972 0.75 GAA (0.45) RAB9AALDH1A1LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116622050-B Low-density wear-resistant anti-skid polyurethane sole resin and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2023-12-05 — — CN claimed
CN-116622050-A Low-density wear-resistant anti-skid polyurethane sole resin and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2023-08-22 — — CN claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
CN-117500800-A (thio) oxazoline insecticide 礼蓝动物保健有限公司 2024-02-02 — — CN disclosed
CN-117430782-A Resin for high-brightness pore-free polyurethane sole, and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2024-01-23 — — CN disclosed
CN-116622050-B Low-density wear-resistant anti-skid polyurethane sole resin and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2023-12-05 — — CN disclosed
CN-116622050-A Low-density wear-resistant anti-skid polyurethane sole resin and preparation method and application thereof 山东一诺威聚氨酯股份有限公司 2023-08-22 — — CN disclosed
CN-116507327-A Chewable formulations 礼蓝动物保健有限公司 2023-07-28 — — CN disclosed
CN-115477737-B Hydrolysis-resistant and flex-resistant polyurethane sole resin composition and preparation and application thereof 山东一诺威聚氨酯股份有限公司 2023-03-31 — — CN disclosed
CN-115477737-A Hydrolysis-resistant and flex-resistant polyurethane sole resin composition and preparation and application thereof 山东一诺威聚氨酯股份有限公司 2022-12-16 — — CN disclosed
US-8454582-B2 Methods and devices for the treatment of ocular conditions SURMODICS, INC. (US) 2013-06-04 — — US disclosed
WO-2006014484-A2 METHODS AND DEVICES FOR THE TREATMENT OF OCULAR CONDITIONS SURMODICS, INC. (US) 2006-02-09 — — WO disclosed
US-20050002865-A1 Diagnostic/therapeutic agents AMERSHAM HEALTH AS (NO) 2005-01-06 — — US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 — — US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 — — US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 — — US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 — — US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 MCHR1 2689/4885NPC1 787/4885RAB9A 1754/4885
US-20050002865-A1 Diagnostic/therapeutic agents FUS, HNRNPF, HNRNPR MCHR1 2626/4885NPC1 1049/4885RAB9A 2303/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 MCHR1 2423/4885NPC1 533/4885RAB9A 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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