Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alloclamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.47 |
| ▸ | DRD2 known ✓ | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 known ✓ | P35462 | 2/20 | 0.47 |
| ▸ | HTR2B known ✓ | P41595 | 2/20 | 0.47 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.47 |
| ▸ | HTR3E known ✓ | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B known ✓ | O95264 | 1/20 | 0.47 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.47 |
| ▸ | DRD4 known ✓ | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.47 |
| ▸ | HTR3A known ✓ | P46098 | 1/20 | 0.47 |
| ▸ | HTR4 known ✓ | Q13639 | 1/20 | 0.47 |
| ▸ | HTR3D known ✓ | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C known ✓ | Q8WXA8 | 1/20 | 0.47 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alloclamide SCHEMBL29730070 | 0.99 | MCHR1 (0.53) | MCHR1RAB9ALMNAALDH1A1ADRA2A | |
| Alloclamide SCHEMBL872157 | 0.99 | MCHR1 (0.53) | MCHR1RAB9ALMNAALDH1A1ADRA2A | |
| Alloclamide SCHEMBL27527103 | 0.97 | MCHR1 (0.51) | MCHR1RAB9ALMNAALDH1A1ADRA2A | |
| SCHEMBL30391813 | 0.88 | HPGD (0.50) | MCHR1RAB9ALMNAALDH1A1CYP1A2 | |
| Alloclamide SCHEMBL8373374 | 0.86 | MCHR1 (0.43) | MCHR1RAB9ALMNAALDH1A1ADRA2A | |
| Flualamide SCHEMBL2734613 | 0.83 | MCHR1 (0.58) | MCHR1RAB9ALMNAALDH1A1SLC22A1 | |
| Flualamide SCHEMBL29804765 | 0.83 | MCHR1 (0.58) | MCHR1RAB9ALMNAALDH1A1SLC22A1 | |
| SCHEMBL6365174 | 0.83 | LIG1 (0.60) | MCHR1LMNAALDH1A1SLC22A1TSHR | |
| SCHEMBL30358593 | 0.82 | GAA (0.53) | RAB9ALMNACYP1A2TSHRGAA | |
| SCHEMBL10656342 | 0.79 | ADRA2A (0.49) | MCHR1RAB9ALMNAALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005094832-A1 | COMPOSITIONS COMPRISING MELOXICAM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-13 | — | — | WO | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| EP-4692178-A1 | CELLULOSE POWDER AND MOLDED BODY | Asahi Kasei Kabushiki Kaisha (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-12427113-B2 | Cellulose composition, tablet, and orally disintegrating tablet | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-09-30 | — | — | US | disclosed |
| WO-2025121315-A1 | CELLULOSE POWDER AND MOLDED BODY | 旭化成株式会社 | 2025-06-12 | — | — | WO | disclosed |
| WO-2025105451-A1 | SOLID PREPARATION | 第一三共ヘルスケア株式会社 | 2025-05-22 | — | — | WO | disclosed |
| WO-2025100523-A1 | METHOD FOR PRODUCING SOLID PREPARATION, AND TABLETS | 第一三共ヘルスケア株式会社 | 2025-05-15 | — | — | WO | disclosed |
| US-12290602-B2 | Cellulose powder, use thereof, and tablets | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-05-06 | — | — | US | disclosed |
| EP-4056637-B1 | CELLULOSE COMPOSITION AND TABLET | ASAHI CHEMICAL IND (JP) | 2025-02-12 | — | — | EP | disclosed |
| WO-2024204699-A1 | CELLULOSE POWDER AND MOLDED BODY | 旭化成株式会社 | 2024-10-03 | — | — | WO | disclosed |
| US-20230055674-A1 | CELLULOSE COMPOSITION AND TABLET | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-02-23 | — | — | US | disclosed |
| US-4954298-A | Method for producing microcapsule | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4917893-A | Prolonged release microcapsules | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0350246-A2 | Sustained release microcapsule for water soluble drug | Takeda Chemical Industries, Ltd. (JP) | 1990-01-10 | — | — | EP | disclosed |
| EP-0145240-B1 | METHOD FOR PRODUCING MICROCAPSULE | Takeda Chemical Industries, Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4711782-A | Prolonged release microcapsules and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-08 | — | — | US | disclosed |
| US-4652441-A | WATER SOLUBLE DRUGS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0190833-A2 | Method for producing microcapsule | Takeda Chemical Industries, Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |
| EP-0145240-A2 | Method for producing Microcapsule | Takeda Chemical Industries, Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |