Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27281513 | 0.81 | TDO2 (0.41) | CA1CA2CA9CA12MAPK1 | |
| SCHEMBL8697134 | 0.79 | CA1 (0.42) | CA1CA2CA9CA12MAPK1 | |
| SCHEMBL22502056 | 0.77 | NAPRT (0.45) | CA1CA2CA9BLMTDP1 | |
| SCHEMBL28026576 | 0.76 | CA2 (0.54) | CA1CA2CA9CA12CYP2C9 | |
| SCHEMBL27685705 | 0.76 | ADORA2A (0.44) | CA1CA2CA9CA12CYP2C9 | |
| SCHEMBL6564249 | 0.74 | ALDH1A1 (0.54) | CA1CA2CA9CA12MAPK1 | |
| SCHEMBL1232419 | 0.72 | ALDH1A1 (0.57) | ADORA2AKMT2AMEN1TDP1GAA | |
| SCHEMBL1094361 | 0.72 | CA1 (0.50) | CA1CA2CA9CA12MAPK1 | |
| SCHEMBL1319393 | 0.71 | ALDH1A1 (0.56) | CYP2C9KMT2ATDP2MEN1BLM | |
| SCHEMBL11882081 | 0.70 | CA2 (0.50) | CA1CA2CA9CA12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250135-A | The preparation method of long-acting dipeptidy peptidase in inhibitors, purposes and its intermediate | 四川科伦药物研究院有限公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-1407973-A | Butynediol Derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2003-04-02 | — | — | CN | disclosed |
| CN-1052484-C | 5-Alkoxy [1,2,4] triazolo [1,5,-C] pyrimidine -2[3H]-thione compounds and their use | DOW AGROSCIENCES LLC (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1243514-A | Sulfonamide derivatives | KOREA RES INST CHEM TECH (KR) | 2000-02-02 | — | — | CN | disclosed |
| CN-1205336-A | 5-Alkoxy [1,2,4] triazolo [1,5,-C] pyrimidine -2[3H]-thione compounds and their use | DOW AGROSCIENCES LLC (US) | 1999-01-20 | — | — | CN | disclosed |
| CN-1041092-C | 5-alkoxy [1, 2, 4] triazolo [1, 5-C ] pyrimidine-2 (3H) -thiones and their use | DOEWLANCO SCIENCE CO (US) | 1998-12-09 | — | — | CN | disclosed |
| CN-1033806-C | Herbicidal composition | DOWELANCO (US) | 1997-01-15 | — | — | CN | disclosed |
| CN-1134223-A | Method for controling needless plant | DOWELANCO (US) | 1996-10-30 | — | — | CN | disclosed |
| CN-1115983-A | 5-alkoxy [1, 2, 4] triazolo [1, 5-C ] pyrimidine-2 (3H) -thiones and their use | DOWELANCO (US) | 1996-01-31 | — | — | CN | disclosed |
| CN-1068824-A | N-pyrazolyl-1, 2, 4-triazolo [1, 5-c ] pyrimidine-2-sulfonamides as herbicides | DOWELANCO (US) | 1993-02-10 | — | — | CN | disclosed |