⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065198 | 0.86 | — | — | |
| SCHEMBL27346583 | 0.81 | TRPV4 (0.40) | — | |
| SCHEMBL30719473 | 0.81 | TRPV4 (0.40) | — | |
| SCHEMBL27346597 | 0.81 | KCNH2 (0.30) | — | |
| SCHEMBL26065174 | 0.77 | — | — | |
| SCHEMBL26065199 | 0.72 | TRPV4 (0.37) | — | |
| SCHEMBL27346630 | 0.71 | — | — | |
| SCHEMBL27346602 | 0.71 | TRPV4 (0.41) | — | |
| SCHEMBL27346641 | 0.71 | TRPV4 (0.41) | — | |
| SCHEMBL25370981 | 0.71 | TRPV4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |