Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 2/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719473 | 1.00 | TRPV4 (0.40) | TRPV4NR1H2NR1H3TSHRSMN1; SMN2 | |
| SCHEMBL27346641 | 0.91 | TRPV4 (0.41) | TRPV4NR1H2NR1H3TSHRSMN1; SMN2 | |
| SCHEMBL27346602 | 0.91 | TRPV4 (0.41) | TRPV4NR1H2NR1H3TSHRSMN1; SMN2 | |
| SCHEMBL26065199 | 0.90 | TRPV4 (0.37) | TRPV4BRS3CXCR3 | |
| SCHEMBL25370981 | 0.88 | TRPV4 (0.38) | TRPV4BRS3 | |
| SCHEMBL30567105 | 0.88 | TRPV4 (0.38) | TRPV4BRS3 | |
| SCHEMBL27346597 | 0.81 | KCNH2 (0.30) | KCNH2SIGMAR1 | |
| SCHEMBL30719552 | 0.81 | TRPV4 (0.39) | TRPV4BRS3 | |
| SCHEMBL30719563 | 0.81 | TRPV4 (0.39) | TRPV4BRS3 | |
| SCHEMBL27346582 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554934-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |