Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | PPARD | Q03181 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | F7 | P08709 | 4/20 | 0.56 |
| ▸ | F3 | P13726 | 4/20 | 0.56 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | FABP4 | P15090 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766940 | 0.91 | GPR84 (0.47) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| SCHEMBL27899376 | 0.89 | GPR84 (0.45) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| SCHEMBL16465358 | 0.82 | EPHX2 (0.58) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL28653654 | 0.81 | FAAH (0.54) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL8004893 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL8736540 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL540326 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL8925859 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL5032813 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 | |
| SCHEMBL18209381 | 0.79 | EPHX2 (0.64) | EPHX2PPARGPPARDPPARAF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103204852-A | Heteroaryl amide analogues as P2X7 antagonists | LUNDBECK & CO AS H | 2013-07-17 | — | — | CN | disclosed |
| CN-101772498-A | As P2X7Heteroaryl amide analogs of antagonists | LUNDBECK & CO AS H | 2010-07-07 | — | — | CN | disclosed |
| CN-1059158-A | Finishing method and composition | REM CHEMICALS INC (US) | 1992-03-04 | — | — | CN | disclosed |