SCHEMBL27348191

SCHEMBL27348191

FC(F)c1cn(Cc2ncc(Cl)cn2)c(-c2ccc(Cl)s2)n1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GRIN2B Q13224 7/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
RXRA P19793 2/20 0.30
GRIN1 Q05586 2/20 0.30
FBP1 P09467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27349228 0.86 GRIN2B (0.32) MEN1ALDH1A1MAPTKMT2AL3MBTL1
SCHEMBL27348270 0.85
SCHEMBL27349311 0.83 GRIN2B (0.35) GRIN2BRXRAGRIN1
SCHEMBL27349314 0.81 CYP11B1 (0.33) MEN1ALDH1A1MAPTKMT2AL3MBTL1
SCHEMBL27348054 0.81 PTGS2 (0.33) ALDH1A1GRIN2BCYP11B1CYP11B2
SCHEMBL27349230 0.81 GRIN2B (0.32) MEN1ALDH1A1MAPTKMT2AL3MBTL1
SCHEMBL27348243 0.80 FBP1 (0.35) ALDH1A1MAPTGRIN2BCYP11B1CYP11B2
SCHEMBL27348256 0.79 GRIN2B (0.32) GRIN2BCYP11B1CYP11B2FBP1
SCHEMBL26088968 0.78 PTGS2 (0.37) ALDH1A1GRIN2BRXRAGRIN1
SCHEMBL30361047 0.77 PTGS2 (0.37) MEN1ALDH1A1KMT2AL3MBTL1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243189-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
EP-4543874-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS Syngenta Crop Protection AG (CH) 2025-04-30 EP disclosed
CN-119325472-A Herbicidal imidazole-containing compounds 先正达农作物保护股份公司 2025-01-17 CN disclosed
WO-2023247358-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-28 WO disclosed
WO-2023247358-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243189-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS DDT, H1-0, H1-4 MEN1 2896/4885ALDH1A1 185/4885MAPT 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.